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Thursday, 14 October 2010 00:04

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 2,100 employees, we operate an extensive scientific program in the field of cancer research.

The Division of Medical Physics in Radiation Oncology (Kst. E040)
is seeking a

PhD Student in Biology
(Ref-No. 102/2010)

The new Heidelberg Ion Therapy Centre (HIT) aims to elucidate the clinical effectiveness of carbon ions for the treatment of cancer. This new irradiation modality may be used separately and in combination with X-rays. Charged particles offer distinct physical and biological properties that enable the application of high local doses to the tumor while sparing the surrounding normal tissue. Moreover, the increased biological effectiveness of carbon ions relative to protons and photons have been shown to improve treatment results for certain tumor entities. The clinical studies will be accompanied by a research program within the frame work of a Clinical Research Group (funded by DFG, see http://www.klinikum.uni-heidelberg.de/Klinische-Forschergruppe-Schwerionentherapie.113071.0.html), which shall develop and integrate new technologies in beam delivery and treatment planning as well as to clarify underlying biological mechanisms.
The Ph.D.-candidate should have a strong interest in performing animal studies to determine the relative biological effectiveness (RBE) of Carbon Ions in the normal central nervous system (CNS). Ultimate goal is to determine a RBE-depth profile for single and fractionated doses of Carbon ions, to monitor functional parameters after irradiation using non-invasive radiological techniques (CT, Ultrasound, MRI etc.) and to study treatment related alterations on the histological and molecular level.

Your profile:
We are looking for a highly motivated student able to work independently and in a team. Diploma or Masters in Biology, Biochemistry or related areas is required. Experience in animal experimentation as well as in histology and molecular biology is required. Experience in tissue processing immunohisto¬chemistry, and microscopy, is of advantage.

Applications should include cover letter, CV, copies of high school exam (e.g. Abitur, Baccalaureat) and university exams and address details of 2 referees.

The position is initially limited for 2 years with the possibility for an extension.

The candidate will be employed by the University Clinic Heidelberg.
For further information please contact Mr. Prof. Dr. Christian Karger, phone 06221 56-38965.

The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

Please send your application to

Im Neuenheimer Feld 280
D-69120 Heidelberg

Or apply preferably online:



Anne Chukwuma
This e-mail address is being protected from spambots. You need JavaScript enabled to view it
German Cancer Research Center

Ansprechpartner: Prof. Dr. Christian Karger



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